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PAHO issues guidelines on disseminated histoplasmosis in HIV/AIDS
June 22 2020
The Pan American Health Organization has issued its first guidelines on both diagnosis and management of disseminated histoplasmosis among people living with HIV, which recommends using antigen testing (which was recently added to the WHO's Essential Diagnostics List)
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Detecting Candida auris in skin and nasal swabs by PCR
June 18 2020
Malczynski and colleagues in Chicago developed a PCR screening test for Candida auris that gave 100% concordance with cultures grown from the same samples, but required the sample to be resuspended in PBS-BSA first - the swab transport medium Amies completely inhibited the PCR reaction
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Itraconazole improves lung function and symptoms in treatment resistant asthma
June 02 2020
While itraconazole is not recommended in current clinical guidelines for severe asthma, evidence is building that some patients may benefit. A new study by Dr Mirsadraee and colleagues in Iran found that it improved asthma control in patients without fungal biomarkers.
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Fungal keratitis among children in North India
May 20 2020
Dr Manisha Singh and colleagues present a series of 104 cases of infectious keratitis in children (<16 years) attending an eye hospital in New Delhi (North India). Of 100 cases in which Gram and KOH smears were performed, microbes were identified in 76%: bacteria alone (40%); fungi only (25%); acanthamoeba only (3%); both bacteria and fungi (8%). The fungi most frequently identified by culture were Fusarium (14 cases), Aspergillus (9 cases) or unidentified dematiaceous (brown-pigmented) fungi (6 cases).
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