Histoplasmosis competes with TB as top killer of Latin American AIDS patients
August 30 2018
Adenis and colleagues in France modelled the annual incidence and deaths from tuberculosis and histoplasmosis among Latin American HIV/AIDS patients. Overall, they estimated 6710 histoplasmosis deaths versus 5062 tuberculosis deaths. In some countries more than 40% of subjects showed previous exposure to Histoplasma capsulatum.
Is it TB or a fungal lung infection? New life saving guidelines released today
August 08 2018
To address this, the Global Action Fund for Fungal infections, GAFFI, convened an expert international panel to develop a workable definition of CPA for resource-constrained countries. In the studies on CPA done to date several different combinations of criteria have been used to define the disease. In most of these studies a CT scan of the chest is necessary, but this facility is not routinely available for the majority of the world’s population
138 million suffer from recurrent vulvovaginal candidiasis, Lancet review reveals
August 03 2018
A new Lancet Infectious Diseases review reveals that 138 million worldwide suffer from recurrent vulvovaginal candidiasis (thrush), a treatable condition whose suffering is compounded by stigma and embarrassment
Early diagnosis protocol for invasive FRS reduces mortality rate from 43% to 17%
July 26 2018
Fungal rhinosinusitis can occasionally invade the eye orbit and brain, giving high mortality rates even with treatment. Dr Ignacio Javier Fernandez and colleagues in Bologna (Italy) showed that a rapid early diagnosis protocol based around nasal endoscopy (rather than histology and microbiology as specified by EORTC) dramatically reduced time delays, disease progression and mortality rates.
Vaginal miconazole and clotrimazole show no additional risk of spontaneous abortion
July 24 2018
Vulvovaginal candidiasis is common during pregnancy but some studies have suggested a link between azole antifungals and increased risk spontaneous abortion. A new study found no significant difference between exposed and non-exposed pregnancies. However, fluconazole appears to have an increased for of spontaneous abortion, stillbirth and Tetralogy of Fallot.